Research Article

Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An In Vivo Study in a Diabetic Animal Model

Table 3

Effects of AG and AG-Gnp on antioxidant defense system activity and pancreatic exocrine function in a diabetic rat model.

GroupMDA (nmol L-1)SOD (U mL-1)CAT (U mL-1)GSH (mg dL-1)AMS (U dL-1)

Control
Diabetic
Diabetic+AG (10 mMg)
Diabetic+AG-GNP (0.5 mM kg-1)
Diabetic+AG-GNP (1 mM kg-1)

AG: aminoguanidine; AG-Gnp: aminoguanidine gold nanoparticle; MDA: malondialdehyde; SOD: superoxide dismutase; CAT: catalase; GSH: reduced glutathione; AMS: amylase. Values are the of 8 independent calculations.