Factors Associated with Promoted Proliferation of Osteosarcoma by Peptidylarginine Deiminase 4

Figure 4

The effect of PADI4 overexpression on the xenograft growth of osteosarcoma in vivo. (a) Images of tumor formation after the mice were injected with cells that had been transfected with PADI4 or vector constructs. (b) Volume detection of xenograft tumor. (c) Weight proportion detection of xenograft tumor. indicated statistical significance. (d) 35 days after injection, mice were killed ultimately, and the tumor tissues were collected for immunohistochemistry staining of PADI4, p-ERK, and active β-catenin.

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