Antitumor Effect of Saikosaponin A on Human Neuroblastoma Cells

Figure 1

The effect of SSA on cell viability of human NB cells SK-N-AS. (a) The chemical structure of SSA. (b) Cell viability of human non-MYCN NB cells SK-N-AS treated by various concentrations of SSA (0, 2.5, 5, 7.5, 10, 12.5, 15, 17.5, or 20 μM) for 24 or 48 hours. (c) Cell viability of human MYCN NB cells SK-N-BE treated by various concentrations of SSA (0, 2.5, 5, 7.5, 10, 15, 20, 30, or 40 μM). (d) Cell viability of normal human cells HBE treated by various concentrations of SSA (0, 5, 10, 20, 40, 80, 120, 160, or 320). The IC₅₀ values were measured (, ).

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