Characterization and Pharmacokinetic Evaluation of Oxaliplatin Long-Circulating Liposomes

Table 3

Fitting parameters of various kinetic models.

Formulation	First-order model		Korsmeyer-Peppas model			Weibull model
	^a	^b		^c	^d		^e
L-OHP	0.9947	1.847	0.9112	72.828	0.186	0.9961	0.580
L-OHP bare lip	0.9993	1.521	0.9109	62.768	0.219	0.9856	0.406
L-OHP PEG lip	0.9902	1.222	0.9377	47.908	0.258	0.9836	0.348

^aCoefficient of correlation; ^bfirst-order constant; ^crelease constant of Korsmeyer-Peppas model; ^ddiffusional exponent; ^eexponent parameter in Weibull model.