3D-QSAR-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Tubulin Inhibitors with Potential Anticancer Activity

Table 1

The score of different parameters of the hypotheses.

S. No.	Hypothesis	Survival score	Survival inactive	Site	Vector	Matches	Activity	Inactive
1	AAARRR.1061	3.870	1.270	0.98	0.992	18	5.640	2.599
2	AAAHRR.319	3.863	1.258	0.98	0.991	18	5.895	2.605
3	AAAHRR.311	3.863	1.258	0.98	0.999	18	5.895	2.605
4	AAHRRR.1415	3.862	1.280	0.97	0.999	18	5.640	2.582
5	AAAHRR.327	3.861	1.280	0.97	0.999	18	5.640	2.581
6	AAAHRR.326	3.861	1.280	0.97	0.999	18	5.513	2.851

A: acceptor; H: hydrophobic; R: aromatic ring.