Research Article

Derangement of Liver Enzymes, Hyperglycemia, Anemia, and Associated Factors among HIV-Infected Patients Treated with Tenofovir Disoproxil Fumarate-Based Regimen in Ethiopia: A Prospective Cohort Study

Table 5

Multivariate binary logistic regression analysis for variables associated with elevated liver enzymes.

VariablesCategoryElevated liver enzymes
ALT
AOR (95% CI)
AST
AOR (95% CI)
ALP
AOR (95% CI)

SexFemaleNANA4.5 (1.03, 19.6)
Age>40 years0.46 (0.02, 9.84)3.49 (0.22, 54.93)1.71 (0.51, 5.71)
BMI>25 kg/m25.51 (0.26, 116.19)2.25 (0.14, 36.91)NA
CD4<200 cells/mm31.39 (0.07, 28.19)0.64 (0.04, 9.76)3.35 (0.97, 11.61)
IsoniazidYes3.49 (0.24, 50.22)2.67 (0.18, 40.02)2.62 (0.48, 14.13)

BMI: body mass index; CD4: cluster of differentiation 4; NA: not applicable. stands for value < 0.05.