circSLC8A1 Acts as a Tumor Suppressor in Prostate Cancer via Sponging miR-21

Figure 4

circSLC8A1 suppressed prostate cancer progression through targeting miR-21. (a) miR-21 mimics significantly reduced the luciferase of wild type circSLC8A1. (b) miR-21 was upregulated in the prostate cancer tissue. (c, d) miR-21 mimics significantly promoted the proliferation of DU145 and PC-3. (e, f) Knockdown of circSLC8A1 enhanced the proliferation ability, but this effect can be partially attenuated by the knockdown of miR-21.

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