Development of Perphenazine-Loaded Solid Lipid Nanoparticles: Statistical Optimization and Cytotoxicity Studies

Table 2

Box-Behnken experimental design runs. Results are given as ().

Independent variables				Dependent variables
No.	Tween 80 conc. () (mg/ml)	Lecithin conc. () (mg)	GMS conc. () (mg)	Size () (nm)	ZP () (mV)	EE () (%)
1	1.25	100	100
2	0.50	200	500
3	0.50	300	300
4	0.50	200	100
5	1.25	200	300
6	2.00	200	100
7	1.25	300	500
8	1.25	100	500
9	0.50	100	300
10	1.25	200	300
11	2.00	300	300
12	2.00	100	300
13	2.00	200	500
14	1.25	300	100
15	1.25	200	300