Development of Perphenazine-Loaded Solid Lipid Nanoparticles: Statistical Optimization and Cytotoxicity Studies

Table 4

Optimized independent variables and the related predicted values, observed response, and prediction error (%) of the optimized formulation. Results are given as ().

(a)

Optimized independent variables				Predicted dependent variables (responses)
No.	Tween 80 conc. () (mg/ml)	Lecithin conc. () (mg)	GMS conc. () (mg)
1	0.5	196.23	500.00	96.39	-25.66	84.13

(b)

Observed responses
Size (nm)		ZP (mV)		EE%
Observed response ()	Prediction error (%)	Observed response ()	Prediction error (%)	Observed response ()	Prediction error (%)
	8.69		10.32		-1.02