Clinical Characteristics, Risk Factors, and Outcomes of Patients with Polymicrobial Klebsiella pneumoniae Bloodstream Infections

Table 3

Risk factors for polymicrobial Klebsiella pneumoniae bloodstream infection by univariate and multivariate analyses.

Variable	Univariate		Multivariate
	OR (95% CI)	value	OR (95% CI)	value
years	0.58 (0.38-0.90)	0.014	0.53 (0.29-0.98)	0.042
Solid tumor	0.48 (0.26-0.86)	0.013	0.81 (0.41-1.60)	0.539
Trauma	1.58 (0.95-2.62)	0.075	1.53 (0.85-2.76)	0.154
CCI	0.89 (0.81-0.98)	0.022	1.11 (0.97-1.28)	0.141
Prior mechanical ventilation	2.10 (1.34-3.29)	0.001	0.99 (0.49-2.00)	0.975
Prior indwelling urinary catheter	3.04 (1.70-5.43)	<0.001	1.29 (0.54-3.06)	0.571
Prior central venous catheter	3.35 (1.84-6.10)	<0.001	1.63 (0.73-3.61)	0.233
Prior surgery	1.50 (0.99-2.25)	0.053	0.70 (0.43-1.15)	0.159
Prior parenteral nutrition	2.04 (1.36-3.08)	0.001	1.455 (0.96-2.51)	0.076
Prior blood transfusion	1.53 (0.92-2.53)	0.100	1.00 (0.57-1.76)	0.987
Prior antimicrobial therapy	2.70 (1.38-5.29)	0.004	0.90 (0.36-2.21)	0.815
Hospitalization ward at BSI onset
General ward	1 (reference)		1 (reference)
Burn ward	12.90 (6.21-26.79)	<0.001	6.13 (2.00-18.76)	0.001
ICU	3.21 (1.85-5.56)	<0.001	2.39 (1.05-5.43)	0.038
Urinary tract infection	0.38 (0.12-1.24)	0.107	0.59 (0.17-2.04)	0.400
Central line-associated infection	1.55 (0.95-2.53)	0.079	0.90 (0.36-2.21)	0.412
Liver abscess	0.16 (0.02-1.17)	0.072	0.38 (0.05-3.17)	0.372
Skin and soft tissue infection	4.62 (2.53-8.43)	<0.001	1.91 (0.77-4.78)	0.164
Healthcare-associated infection	2.60 (1.11-6.10)	0.028	0.68 (0.22-2.12)	0.508

OR: odds ratio; CI: confidence interval; CCI: Charlson comorbidity index; ICU: intensive care unit.