Donor Preconditioning with Inhaled Sevoflurane Mitigates the Effects of Ischemia-Reperfusion Injury in a Swine Model of Lung Transplantation

Table 1

GEE analysis of association between lung function parameters over time and the control and SEV groups.

Parameters		SEV vs. control	Time	Interaction ()
PaO2/FiO2	Coef.	6.362	-1.379	-12.806
	value	0.915	0.398	<0.001
pH	Coef.	0.198	-0.001	-0.011
	value	0.578	0.882	<0.001
PaCO2	Coef.	0.776	-0.061	1.856
	value	0.879	0.774	<0.001
BE	Coef.	2.295	-0.097	—
	value	0.022	0.01	—
Lactate	Coef.	-0.546	-0.013	-0.096
	value	0.55	0.629	0.018
Ht	Coef.	0.801	0.335	0.358
	value	0.539	0.568	<0.001
Compliance	Coef.	0.865	-0.233	-0.134
	value	0.682	<0.001	0.054
MAP	Coef.	-5.788	-0.951	—
	value	0.326	<0.001	—
HR	Coef.	-12.739	-0.643	3.536
	value	0.134	0.092	<0.001
SpO2	Coef.	-0.265	0.061	-0.631
	value	0.912	0.607	<0.001
PIP	Coef.	-0.674	0.235	—
	value	0.69	<0.001	—
PlatP	Coef.	-0.012	0.256	—
	value	0.995	<0.001	—
PAPs	Coef.	1.066	-0.161	0.384
	value	0.693	0.119	0.013
PAPd	Coef.	-1.727	-0.184	0.236
	value	0.377	0.009	0.025
PCWP	Coef.	-1.065	-0.148	—
	value	0.491	<0.001	—
CO	Coef.	0.305	-0.039	—
	value	0.476	0.002	—
CI	Coef.	0.709	-0.031	—
	value	0.135	0.030	—
CVP	Coef.	-2.729	-0.181	0.032
	value	0.034	0.001	<0.001

( value < 0.05). The value represent the result of GEE model with exchangeable correlation.