Gardnerella vaginalis and Neisseria gonorrhoeae Are Effectively Inhibited by Lactobacilli with Probiotic Properties Isolated from Brazilian Cupuaçu (Theobroma grandiflorum) Fruit

Table 5

Metabolomic analysis of CFCS.

Retention time (min)	Substance	MRS area (%)	CFCS area (%)	CFCS area (%)	CFCS area (%)	CFCS area (%)	CFCS area (%)
			Lc24	Lf38	Lf47	Lp81	Lp90
4.164	Carbodiimide	—	1.48	0.74	0.89	1.51	1.37
4.700	N.N-Dimethylglycine	0.04	—	0.03	—	0.08	—
7.295	Lactic acid	0.85	61.77	49.18	56.43	57.64	61.05
7.524	Acetic acid	—	—	0.05	0.07	—	0.04
7.531	2-Hydroxyetanoic acid	—	—	—	—	0.04	—
7.768	Valine	0.05	—	—	—	—	—
8.405	Alanine	1.14	2.15	4.09	3.40	2.24	2.00
9.020	Glycine	0.33	0.81	1.11	0.82	0.99	0.77
9.873	β-Lactate	—	—	0.08	0.10	0.06	0.07
10.168	Leucine	0.17	—	—	—	—	—
10.445	3-Hydroxybutyric acid	—	—	—	—	0.04	—
10.638	α-Hydroxyvaleric acid	—	0.17	—	—	0.10	0.16
12.465	Valine	1.02	1.71	2.85	2.95	2.12	2.06
13.203	4-Methyl-2-hydroxypentanoic acid	—	0.35	0.87	0.71	0.29	0.58
13.395	3-Methyl-2-hydroxypentanoic acid	—	—	—	—	0.07	0.10
14.510	Leucine	2.48	2.55	3.45	4.49	3.50	3.43
14.733	Glycerol	—	0.71	—	1.34	—	—
14.769	Phosphoric acid	7.29	7.56	11.13	9.73	7.85	7.86
15.236	Isoleucine	1.18	1.89	2.65	2.74	2.17	2.15
15.308	γ-Amino butyric acid	—	—	0.10	—	0.14	—
15.839	Butanoic acid	0.20	0.28	0.97	1.00	0.46	0.50
16.220	2-Methyl-2.3-dihydroxypropanoic acid	0.10	0.13	0.27	0.36	0.15	0.16
16.705	Pyrimidine	—	—	0.13	—	—	—
17.644	Serine	0.75	0.85	2.23	1.19	0.61	0.47
18.148	Butanoic acid	0.02	0.12	0.09	0.11	0.06	0.07
18.272	3-Methyl-1.4-dihydroxypiperazine-2.5-dione	—	0.79	0.08	—	0.07	—
18.496	Butyric acid	—	—	2.07	—	—	—
18.531	Threonine	0.62	—	—	1.71	1.38	1.24
18.555	Lactic acid dimer	—	0.52	—	—	0.25	0.27
19.332	2.4-Dihydroxybutanoic acid	—	—	0.12	0.15	0.07	0.07
19.494	Aspartic acid	—	1.04	—	0.64	—	0.64
21.091	Trisiloxane	—	0.11	0.15	0.15	0.11	0.13
21.769	Malic acid	—	0.12	—	—	0.10	0.24
21.865	2-Pyrrolidone-5-carboxylic acid	—	0.34	—	0.58	—	0.81
22.262	Glutamic acid	—	—	—	0.15	—	—
22.458	Methionine	0.22	—	0.27	—	0.31	—
22.588	Proline	1.40	1.17	3.55	0.84	2.20	1.52
22.708	Aspartic acid	0.56	—	0.63	—	0.90	0.20
23.099	Phenylalanine	—	0.92	—	1.29	—	0.59
24.376	Benzenepropanoic acid	—	0.09	0.57	0.45	0.28	0.50
25.371	Ornithine	—	—	—	—	0.21	—
25.583	Glutamine	1.76	—	3.81	—	3.06	1.40
26.434	Tartaric acid	0.34	0.40	0.67	0.47	0.49	0.54
26.995	Hydroxy 4-oxo-2.4-di(hydroxylamine)butanoate	—	—	—	—	0.16	—
27.048	Asparagine	0.04	—	0.36	—	—	—
27.895	Lysine	—	—	1.22	—	1.11	—
28.638	Arabinitol	—	—	0.10	—	—	—
28.805	Ribitol	—	—	—	—	0.11	0.12
29.803	2.3-Dihydroxypropylphosphoric acid	0.13	0.11	0.30	0.26	0.26	0.25
29.920	D-Ribo-Hexonic acid	—	—	—	—	0.09	0.11
30.946	2-Keto-D-gluconic acid	0.7	—	—	—	0.06	—
31.133	1,2,3-Propanetricarboxylic acid	—	6.15	0.11	—	—	—
31.259	Citric acid	7.49	—	—	—	6.66	5.91
32.345	Pentanedioic acid	—	0.34	0.75	0.16	0.29	—
32.451	Benzenepropanoic acid	0.10	—	—	—	—	—
32.879	4-Hydroxyphenyllactic acid		—	—	0.07	0.10	0.16
33.891	Tyrosine	0.13	—	—	—	—	0.40
33.955	Glucitol	0.04	0.16	3.65	2.76	—
35.660	Inositol	31.07	—	0.07	—	—	0.07
39.845	Tryptophan	0.06	—	0.26	—	0.16	—
—	Sugars	38.12	3.38	4.07	2.96	0.83	1.54
—	Unidentified compounds	1.60	1.81	1.20	3.83	0.62	0.46
—	Identified compounds (except sugars)	60.28	94.81	94.73	93.21	98.55	98.00
—	Total	100.00	100.00	100.00	100.00	100.00	100.00