Research Article

Evaluation of Thymic Output and Regulatory T Cells in Kidney Transplant Recipients with Chronic Antibody-Mediated Rejection

Table 1

Demographic and clinical characteristics of the patients.

VariablescAMR group ()SGF group () value

Age (years)41.32 (14.62)39.15 (10.17)0.57
40 [30.00, 51.50]39 [34.00, 41.00]
Sex (women)9 (32.14)6 (30.00)0.88
Post-TX time59.71 (64.39)62.80 (35.92)0.37
39.00 [2.25, 84.00]60.00 [36.00, 84.00]
Weight (kg)71.42 (17.24)73.60 (9.79)0.62
72.50 [57.75, 83.25]74.50 [73.00, 81.50]
FBS (mg/dl)121.35 (81.24)115.45 (50.67)0.81
97.00 [86.50, 114.50]100.50 [94.00, 116.00]
Triglycerides (mg/dl)120.00 (56.72)131.70 (73.11)0.53
110.50 [90.00,145.00]131.50 [95.00, 145.50]
Cholesterol (mg/dl)151.17 (30.12)173.05 (51.29)0.07
150.00 [131.50, 165.50]173.00 [151.50, 186.50]
HDL (mg/dl)47.54 (16.94)47.00 (17.25)0.96
47.00 [36.00, 57.50]47.00 [41.00, 55.50]
LDL (mg/dl)82.96 (26.16)87.10 (40.59)0.66
84.00 [70.50, 102.00]87.00 [62.00, 98.00]
Sodium (Meq/I)136.89 (6.03)140.63 (3.16)0.02
136.50 [134.50, 140.50]141.00 [139.00, 142.00]
Potassium (Meq/I)4.40 (0.84)4.32 (1.18)0.79
4.35 [4.00, 4.90]4.19 [3.80, 4.30]
Phosphorus (mg/dl)5.11 (1.69)3.69 (0.90)0.001
4.90 [3.90, 5.80]3.70 [3.15, 3.84]
Calcium (mg/dl)8.40 (0.87)9.27 (0.31)<0.001
8.55 [7.75, 9.00]9.30 [9.15, 9.45]
Uric acid (mg/dl)7.69 (2.61)5.58 (1.51)0.002
7.35 [6.15, 9.15]5.50 [4.95, 5.85]
Urea (mg/dl)83.75 (42.39)41.16 (16.93)<0.001
89.50 [53.00, 108.50]39.00 [30.00, 48.00]
BUN (mg/dl)37.68 (1.88)25.70 (14.41)0.02
41.80 [23.65, 48.48]23.28 [25.96, 28.60]
eGFR (ml/min/1.73 m2)21.35 (17.06)63.17 (16.13)<0.001
13.81 [10.34, 29.36]63.53 [58.85, 71.97]
Creatinine (mg/dl)4.41 (2.31)1.31 (0.66)<0.001
4.10 [2.55, 6.26]1.18 [1.07, 1.30]
WBC (103/μl)7.44 (3.41)6.66 (1.20)0.33
6.30 [5.20, 9.20]6.60 [5.70, 7.50]
Platelet (103/μl)185.03 (86.59)218.20 (60.23)0.15
180.50 [125.00, 229.50]218.00 [206.00, 263.00]
Lymphocyte (%)20.24 (8.34)25.00 (3.99)0.02
21.41 [14.00, 26.00]25.00 [25.00, 25.00]
Hemoglobin (g/dl)9.98 (2.14)13.48 (2.97)<0.001
9.75 [8.15, 11.47]13.85 [13.50, 15.30]
Hematocrit (%)32.02 (7.23)40.27 (7.42)<0.001
30.50 [27.20, 34.75]40.20 [38.55, 46.25]

Scale and nominal variables were depicted as mean (SD) and median [Q1; Q3] and number (percent), respectively. The Mann–Whitney test was used for the evaluation of intergroup differences. Abbreviations: cAMR: chronic antibody-mediated rejection; SGF: stable graft function; FBS: fasting blood sugar; HDL: high-density lipoprotein; LDL: low-density lipoprotein; BUN: blood urine nitrogen; eGFR: estimated glomerular filtration rate; WBC: white blood cell.