Impact of Albendazole on Cytokine and Chemokine Response Profiles in Echinococcus multilocularis-Inoculated Mice

Table 3

Relative mRNA expressions of specific transcription factors and functional cytokines of T cell subtypes in splenic cell suspension.

Item/group	Control+ABZ	AE+ABZ	Control +CMC	AE+CMC	value
INF-γ					>0.05
IL-2					>0.05
IL-4					>0.05
IL-10					>0.05
IL-17A					>0.05
T-bet	^♠Δ		^♠	^Δ	<0.05
GATA3					>0.05
T-bet/GATA3	^Δ	^♦		^Δ♦	<0.05
RORγτ					>0.05
FoxP3					>0.05
RORγτ/FoxP3					>0.05
TLR2					<0.05
TLR4					<0.05

The control+CMC group vs. AE+CMC group; ^Δthe control+ABZ group vs. AE+ABZ group; ^♠the control+ABZ group vs. AE+CMC group. Abbreviations: ABZ: albendazole; CMC: carboxymethyl cellulose; AE: alveolar echinococcosis; IL: interleukin; GRO: growth-related oncogene; IP: interferon- (IFN-) γ-induced protein; MCP: monocyte chemoattractant protein; MIP: macrophage inflammatory protein.