Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy

<div>QUE treatment upregulates autophagy in NPCs. (a) Western blot analysis of the autophagy-related proteins, Beclin-1 and p62, and LC3 II/I. (b) Quantification of Beclin-1, p62, and LC3 II/I protein levels. (c) Representative TEM image showing the autophagic changes in NPCs after various treatments. Black arrow: autophagosome; white arrow: autophagolysosome. Original magnification ×30000, scale bar: 500 nm. 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BioMed Research International

fig3

Figure 3

Figure 3: Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy 