BioMed Research International / 2021 / Article / Tab 9 / Research Article
Shared Molecular Mechanisms between Alzheimer’s Disease and Periodontitis Revealed by Transcriptomic Analysis Table 9 The 12 overlapping genes between 48 feature selection-obtained crosstalk genes and periodontitis-related genes in the DisGeNET database. Among the 12 genes, 6 genes, C4A, C4B, CXCL12, FCGR3A, IL1B, and MMP3, were associated with chronic periodontitis.
Gene symbol Gene ID Disease ID Disease name C3 718 C0031099 Periodontitis C4A 720 C0266929 Chronic periodontitis C4B 721 C0266929 Chronic periodontitis CXCL12 6387 C0266929 Chronic periodontitis FCGR3A 2214 C0266929 Chronic periodontitis FCGR3A 2214 C0031099 Periodontitis FCGR3A 2214 C0031106 Periodontitis, juvenile FCGR3A 2214 C0399447 Early-onset periodontitis FCGR3A 2214 C0031030 Periapical periodontitis FCGR3B 2215 C0399447 Early-onset periodontitis FCGR3B 2215 C0031106 Periodontitis, juvenile HSPB1 3315 C0031030 Periapical periodontitis IL1B 3553 C1719494 Periodontitis, localized aggressive IL1B 3553 C1719495 Aggressive periodontitis, generalized IL1B 3553 C0399447 Early-onset periodontitis IL1B 3553 C0001342 Acute periodontitis IL1B 3553 C0031106 Periodontitis, juvenile IL1B 3553 C0031030 Periapical periodontitis IL1B 3553 C4025886 Severe periodontitis IL1B 3553 C0031099 Periodontitis IL1B 3553 C0266929 Chronic periodontitis MME 4311 C0031099 Periodontitis MMP3 4314 C0031106 Periodontitis, juvenile MMP3 4314 C0001342 Acute periodontitis MMP3 4314 C0266929 Chronic periodontitis MMP3 4314 C0031099 Periodontitis PLAT 5327 C1719495 Aggressive periodontitis, generalized VEGFA 7422 C0031099 Periodontitis
