Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats

<div>T cell profiles of PBMCs in juvenile recipient WKY and SHR for 4 days after transferring Th17 cells from adult donor SHR. Representative flow cytometric analysis revealed the proportion of (a) CD4<sup>+</sup>IL-17A<sup>+</sup> (Th17) cells and (b) CD4<sup>+</sup>FoxP3<sup>+</sup> (Treg) cells of PBMCs in juvenile recipient WKY or SHR. (c) Quantification revealed that CD4<sup>+</sup>IL-17A<sup>+</sup> (Th17) cells after the transfer of Th17 cells significantly increased compared with the vehicle in juvenile recipient WKY and SHR. (d) Quantification revealed that the proportion of CD4<sup>+</sup>FoxP3<sup>+</sup> (Treg) cells after transfer of Th17 cells significantly increased compared with the vehicle in juvenile recipient SHR. 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BioMed Research International

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Figure 4

Figure 4: Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats 

Figure 4 | Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats 