Genetic Variants of lncRNA GAS5 Contribute to Susceptibility of Ischemic Stroke among Southern Chinese Population

Table 6

The relationship between lncRNA GAS5 rs145204276 variant and IS subtypes in IS patients.

	lncRNA GAS5 rs145204276
	Genotype			value^a	Allele		value^a	OR (95% CI)
	II	ID	ID		I	D
Control	486 (46.5)	465 (44.5)	94 (9.0)		1437 (68.8)	653 (31.2)
Cases
LAA	265 (38.5)	335 (48.6)	89 (12.9)	0.0040	865 (62.8)	513 (37.2)	0.0010	1.31 (1.13-1.51)
SAO	122 (40.5)	149 (49.5)	30 (10.0)	0.18	393 (65.3)	209 (34.7)	0.15	1.17(0.97-1.42)
CE	18 (46.2)	14 (35.9)	7 (17.9)	0.18	50 (64.1)	28 (35.9)	0.39	1.23(0.77-1.98)
UE	19 (33.3)	30 (52.6)	8 (14.1)	0.18	68 (59.6)	46 (40.4)	0.098	1.49(1.01-2.19)

CE: cardioembolic; CI: confidence interval; DD: del/del; GAS5: growth arrest special 5; ID: ins/del; II: ins/ins; IS, ischemic stroke; LAA: large-artery atherosclerosis; lncRNA: long noncoding RNA; OR, odds ratio; SAO: small-artery occlusion; UE: unspecified aetiology. ^aFalse discovery rate-adjusted P value for multiple hypotheses testing using the Benjamini-Hochberg method. P <0.05 is indicated in bold font.