BioMed Research International

Research Article

Genetic Variants of lncRNA GAS5 Contribute to Susceptibility of Ischemic Stroke among Southern Chinese Population

Table 7

The relationship between lncRNA GAS5 rs55829688 variant and IS stratified by TOAST classification in IS patients.


	lncRNA GAS5 rs55829688
	Genotype			value^a	Allele		value^a	OR (95% CI)
	TT	TC	CC	value^a	T	C	value^a	OR (95% CI)

Control	517 (49.5)	430 (41.1)	98 (9.4)		1464 (70.0)	626 (30.0)
Cases
LAA	384 (56.0)	250 (36.0)	55 (8.0)	0.16	1018 (73.9)	360 (26.1)	0.064	0.83 (0.71-0.96)
SAO	154 (51.2)	119 (39.5)	28 (9.3)	0.91	427 (70.9)	175 (29.1)	0.91	0.96 (0.79-1.17)
CE	20 (51.3)	15 (38.5)	4 (10.3)	0.91	55 (70.5)	23 (29.5)	0.92	0.98 (0.60-1.61)
UE	21 (36.8)	31 (54.4)	5 (8.8)	0.26	73 (64.0)	41 (36.0)	0.34	1.31 (0.89-1.95)

CE: cardioembolic; CI: confidence interval; GAS5: growth arrest special 5; IS: ischemic stroke; LAA: large-artery atherosclerosis; lncRNA: long noncoding RNA; OR, odds ratio; SAO: small-artery occlusion; UE: unspecified aetiology. ^aFalse discovery rate-adjusted value for multiple hypotheses testing using the Benjamini-Hochberg method.