Research Article
UPLC-MS/MS for the Herb-Drug Interactions of Xiao-Ai-Ping Injection on Enasidenib in Rats Based on Pharmacokinetics
Table 3
The stability of enasidenib in rat plasma (
, ).
| | Added (ng/mL) | Room temperature, 2 h | Autosampler 4 °C, 4 h | Three freeze-thaw | -20°C, 4 weeks | | RSD (%) | RE (%) | RSD (%) | RE (%) | RSD (%) | RE (%) | RSD (%) | RE (%) |
| | 2.5 | 7.01 | -3.53 | 6.45 | 1.35 | 6.02 | -1.00 | 4.45 | 1.07 | | 250 | 7.07 | 2.26 | 5.38 | -1.59 | 5.44 | 1.85 | 5.18 | -0.55 | | 750 | 1.99 | -0.42 | 2.54 | 0.33 | 1.63 | 0.18 | 1.26 | -0.31 |
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