Oral Health, Caries Risk Profiles, and Oral Microbiome of Pediatric Patients with Leukemia Submitted to Chemotherapy

Table 4

Caries-related factors in children with acute lymphoblastic leukemia and healthy controls.

Variables	Cut-off value	HC ()	ALL ()	value
Diet content	Very low sugar consumption	18	6	0.002
	Low sugar consumption	10	10
	Moderate sugar consumption	8	17
	High sugar consumption	3	6
Diet frequency	<3/day	3	1	0.003
	3~5/day	32	23
	>5/day	4	15
Plaque index				0.008^#
Streptococcus mutants	<104 CFU/ml	16	22	0.146
	10^4~105 CFU/ml	17	14
	10^5~106 CFU/ml	3	1
	>10^6 CFU/ml	3	2
Fluoride program	0	7	1	0.006
	1	10	4
	2	14	20
	3	8	14
Stimulated saliva secretion rate	Ml/min,			0.017^#
Salivary buffer capacity	Low	0	0	0.190
	Medium	7	12
	High	32	27

ALL: patients with acute lymphoblastic leukemia; HC: healthy controls. ^#Unpaired test was used. Independent sample nonparametric Mann-Whitney test was used.