Effects of miRNA-140 on the Growth and Clinical Prognosis of SMMC-7721 Hepatocellular Carcinoma Cell Line

Figure 7

Predictive target gene and GO annotation and KEGG pathway enrichment analysis. (a) The Wayne diagram of the intersection of predictive genes. Pink is the predictive gene set of the miRDB database, yellow is the predictive gene set of the miRTarBase database, green is the predictive gene set of the miRWalk database, and purple is the predictive gene set of the TargetScan database. (b) The interaction network between miRNA-140 and mRNA; the purple triangle shows miRNA-140, and the blue dot shows the mRNA interacting with miRNA-140. (c) The GO function annotation of 36 target genes interacting with each other. Green represents a molecular function (MF), blue represents cell component (CC), and red represents the biological process (BP). (d) The enrichment analysis of KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway of 36 target genes interacting with each other.

(a)

(b)

(c)

(d)