Development of the Binary and Ternary Atorvastatin Solid Dispersions: In Vitro and In Vivo Investigations

Table 2

Phase solubility of ATR in the presence of different concentrations of PEG 10000 and poloxamer 188 in water and PBS.

(a)

ATR phase solubility in the presence of increasing concentrations of carriers in water (μg/ml) ()
Concentration (%) ()	PEG 10000	Poloxamer 188	10% PEG 10000 plus increasing concentrations of poloxamer 188
0%
2.5%
5%
7.5%
10%

(b)

ATR phase solubility in the presence of increasing concentrations of carriers in PBS (μg/ml) ()
Concentration (%) ()	PEG 10000	Poloxamer 188	10% PEG 10000 plus increasing concentrations of poloxamer 188
0%; 2.5%
	5%
7.5%
10%