Research Article
Correlations between FTO Gene Polymorphisms and TSH Level in Uyghur Chinese Patients with Type 2 Diabetes
Table 2
Association between FTO rs8050136 and rs9939609 and the TSH level in study participants.
| | SNP | Group | Allele | Genotype | Dominant model | Recessive model | | C | A | CC | CA | AA | CC | CA+AA | CC+CA | AA | | rs8050136 | TSH-0 () | 460 (67.06) | 226 (32.94) | 156 (45.48) | 148 (43.15) | 39 (11.37) | 156 (45.48) | 187 (54.52) | 304 (88.63) | 39 (11.37) | | TSH-1 () | 210 (72.92) | 78 (27.08) | 74 (51.39) | 62 (43.06) | 8 (5.56) | 74 (51.39) | 70 (48.62) | 136 (94.45) | 8 (5.56) | | 3.246 | 4.303 | 1.42 | 3.933 | | 0.720 | 0.116 | 0.233 | 0.047 |
| | Group | Allele | Genotype | Dominant model | Recessive model | | T | A | TT | TA | AA | TT | TA+AA | TT+TA | AA | | rs9939609 | TSH-0 () | 447 (65.74) | 233 (34.26) | 151 (44.41) | 145 (42.65) | 44 (12.94) | 151 (44.41) | 189 (55.59) | 296 (87.06) | 44 (12.94) | | TSH-1 () | 198 (71.74) | 78 (28.26) | 68 (49.28) | 62 (44.92) | 8 (5.80) | 68 (49.28) | 70 (50.72) | 130 (94.20) | 8 (5.80) | | 3.224 | 5.23 | 0.935 | 5.167 | | 0.073 | 0.073 | 0.333 | 0.023 |
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