MicroRNA Biomarkers of High-Grade Cervical Intraepithelial Neoplasia in Liquid Biopsy

Table 1

Clinical features of the investigated patients.

	Features	HFS ()	CIN 3 ()	value
Age, years	Median (min-max)	42 (32-69)	35 (19-48)	0.036
		Value, (%)	Value, (%)
Categorized age	<30 years	−	6 (30.0%)
	30–49 years	8 (72.7%)	14 (70.0%)
	>50 years	3 (27.3%)	−
hr-HPV	Negative	7 (63.7%)	1 (5.0%)
	HPV 16	−	5 (25.0%)
	HPV 18	−	1 (5.0%)
	HPV others	4 (36.3%)	8 (40.0%)
	HPV 16 + others	−	5 (25.0%)

HFS: healthy female subjects without cervical intraepithelial neoplasia (CIN); CIN 3: cervical intraepithelial neoplasia grade 3; hr-HPV: high-risk human papillomavirus; Min: minimum; Max: maximum. The Mann–Whitney test was performed to evaluate age between the biological groups. .