MicroRNA Biomarkers of High-Grade Cervical Intraepithelial Neoplasia in Liquid Biopsy

Table 2

Sensitivity, specificity, AUC, fold change, and value of differentially expressed miRNAs between CIN 3 and HFS samples.

miRNA	Sensitivity	Specificity	AUC	Fold change	value
miR-381-3p	64%	70%	0.77	-2.1607	0.0043
miR-4531	73%	70%	0.77	-2.1607	0.0047
miR-205-5p	70%	91%	0.78	3.6693	0.0100
miR-130a-3p	75%	55%	0.78	3.0042	0.0078
miR-3136-5p	90%	73%	0.77	2.0138	0.0057
miR-128-2-5p	70%	73%	0.77	2.4596	0.0048
let-7f-5p	80%	82%	0.77	2.0138	0.0320
miR-202-3p	65%	82%	0.77	3.0042	0.0078
miR-323a-5p	45%	100%	0.75	2.0138	0.0089

Significant () student’s t-test results from the comparison of the miRNA expression levels between the biological groups. AUC: area under the curve. .