Review Article

Application of Multiparametric Intraoperative Ultrasound in Glioma Surgery

Table 4

Summary of the applications of ultrasound elastography (UE) for glioma.

YearFirst author and countryPatient No.GradeStudy endpointsResults

2019Cepeda et al. (Spain) [17]36HGG 4
LGG 16
Others 16
To determine the elastographic patterns of different brain tumor types and establish differences between their peritumoral regionsWe objectively described the elastographic patterns of different types of brain tumors. We identified differences in both the tumors and peritumoral areas according to histologic types
2019Prada et al. (Italy) [79]64HGG 38
LGG 7
Others 19
To describe the first large-scale implementation of strain elastography (SE) in oncological neurosurgery for lesions discrimination and characterizationSE allows clinicians to understand the mechanical properties of the brain and lesions during examination and permits better discrimination between different tissues compared to B-mode. Additionally, SE can differentiate between LGG and HGG
2016Chauvet et al. (France) [78]63HGG 18
LGG 14
Others 31
To characterize elasticity of the normal brain parenchyma and brain tumors using shear-wave elastography (SWE)Significant differences in elasticity were observed among the most common types of brain tumors. With intraoperative SWE, neurosurgeons may acquire innovative information to establish a diagnosis and guide resection