Research Article

[Retracted] Multiomics Analysis of Transcriptome, Epigenome, and Genome Uncovers Putative Mechanisms for Dilated Cardiomyopathy

Figure 9

Validation of the expression of mutant genes in blood and left ventricle of DCM. (a) Principal component analysis for 8 DCM and control blood samples from the GSE101585 dataset. Blue: DCM samples and green: healthy samples. (b) Heat map visualizing the correlation between DCM and control blood groups. The intensity of the color is proportional to the correlation coefficient. (c) Scatter plots showing up- and downregulated genes between DCM and control blood groups. (d) Volcano plots depicting all DEGs between the two groups. (e) Heat map visualizing the expression patterns of DEGs between the two groups. Red: upregulation; blue: downregulation. (f) Differences in expression of AHNAK2, MAML3, MUC4, OR2T35, and PHLDA1 between DCM and control blood samples in the GSE101585 dataset. (g) Abnormal expression of AHNAK2, MAML3, and PHLDA1 between DCM and control left ventricle samples in the GSE141910 dataset. (h) Dysregulated expression of AHNAK2, MAML3, MUC4, and PHLDA1 between DCM and control left ventricle samples in the GSE126569 dataset.
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