Research Article

Safety Evaluation and Flow Modification in the Anterior Cerebral Artery after Pipeline Embolization Device Deployment across the Internal Carotid Artery Terminus

Table 1

Baseline demographic data for all, group 1, and group 2 patients.

CharacteristicAllGroup 1 ()Group 2 () value

Sex0.52
 M (%)17 (35%)5 (29.4%)12 (38.7%)
 F (%)31 (65%)12 (71.0%)19 (61.3%)
Mean age in yrs0.26
Hypertension (%)12 (25%)6 (35.3%)6 (19.4%)0.30
Diabetes (%)4 (8.3%)2 (11.8%)2 (6.5%)0.52
Smoking (%)14 (29.2%)3 (17.6%)11 (35.5%)0.32
Aneurysm size (mm)0.08
Aneurysms at the ICAb (%)15 (31.3%)8 (47.0%)7 (22.5%)0.08
Treatment0.15
 PED (%)32 (62.7%)13 (76.5%)19 (55.9%)
 PED+coil (%)19 (37.3%)4 (23.5%)15 (44.1%)
Aneurysm occlusion0.008
 Complete obliteration (%)31 (60.8%)6 (35.3%)25 (73.5%)
 IAO (%)20 (39.2%)11 (64.7%)9 (26.5%)
Fate of A1
 Occlusion (%)11 (22.9%)11 (35.5%)
 Diminished flow (%)20 (41.7%)20 (64.5%)
 No flow change (%)17 (35.4%)17 (100%)
 I-A1/I-ICA (mean (SD))0.50 (0.12)0.49 (0.11)0.51 (0.12)0.74
 I-M1/I-ICA (mean (SD))0.76 (0.12)0.77 (0.12)0.76 (0.12)0.78
 I-A1/I-M1 (mean (SD))0.67 (0.19)0.67 (0.22)0.68 (0.17)0.88
 OR I-A1/C-A1 (mean (SD))0.92 (0.24)0.91 (0.19)0.93 (0.27)0.81
 sPED/I-ICA (mean (SD))1.11 (0.16)1.19 (0.18)1.06 (0.12)0.006

yrs: years; M: male; F: female; ICAb: the internal carotid artery bifurcation; PED: pipeline embolization device; IAO: incomplete aneurysm occlusion; I-A1: ipsilateral-A1; I-ICA: ipsilateral internal carotid artery; SD: standard deviation; I-M1: ipsilateral-M1; OR: the odds ratio; C-A1: contralateral-A1; sPED: the PED size.