Electroacupuncture Improves Pregnancy Outcomes in Rats with Thin Endometrium by Promoting the Expression of Pinopode-Related Molecules

Figure 6

The mechanism of electroacupuncture (EA) improves embryo implantation by regulating the expression of pinopode-related molecules. EA has a positive effect on the endometrial receptivity of thin endometrium model rats by improving pinopode formation through multiple molecular targets. After EA treatment in thin endometrial model rats, the embryo implantation rate is improved, endometrial structure is repaired, the formation of pinopodes on the endometrium is increased, and the expression of pinopode-related molecules, including integrin αvβ3, HOXA10, HBEGF, ERα, and PR, is upregulated. In addition, regulation of ERα and PR may affect the expression of HOXA10 and HBEGF.