Research Article

Real-World Study of Cisplatin, Etoposide, and Bleomycin Chemotherapy Regimen in Gestational Trophoblastic Neoplasia

Table 2

Efficacy of BEP chemotherapy in GTN patients ().

N (percentile)Primary treatment group ()Salvage treatment group ()

Course of BEP4 (3, 5)3 (2, 4)
Additional treatment15 (22.7)10 (34.5)
 Hysterectomy12 (18.2)6 (20.7)
 UAE3 (4.5)0 (0)
 Radiation1 (1.52)1 (3.4)
 Lobectomy0 (0)2 (6.9)
 Hysteroscopic lesion resection0 (0)1 (3.4)
Response
 CR58 (87.9)24 (82.8)
 PR8 (12.1)5 (17.2)
Reasons to change BEP regimen17 (25.8)8 (27.6)
 Resistance8 (12.1)5 (17.2)
 Nontolerable3 (4.5)3 (10.3)
 Strengthen for no bleomycin or restriction6 (9.1)0 (0)

Note: BEP: cisplatin, etoposide, and bleomycin; GTN: gestational trophoblastic neoplasia; UAE: uterine artery embolism; CR: complete remission; PR: partial remission.