Research Article

[Retracted] Identification and Validation of Key Genes in Hepatocellular Carcinoma by Bioinformatics Analysis

Table 4

The aliases and gene function of 5 key genes.

Gene symbolAliasesGene function

CDK1CDC2, CDC28A, P34CDC2This gene is essential for G1/S and G2/M phase transitions of the eukaryotic cell cycle.
NDC80HEC, HEC1, TID3, KNTC2, HsHec1, hsNDC80The gene encodes proteins necessary for proper chromosome segregation.
HMMRCD168, IHABP, RHAMMThe protein encoded by this gene is involved in cell motility and potentially associated with a higher risk of breast cancer.
CDKN3CDKN3, CDI1, CIP2, KAPThe protein encoded by this gene belongs to the dual-specificity protein phosphatase family. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers.
PTTG1EAP1, HPTTG, MGC126883, MGC138276, PTTG, TUTR1The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression.