Abnormal Expression and Prognostic Significance of Bone Morphogenetic Proteins and Their Receptors in Lung Adenocarcinoma

Figure 4

The nomogram to anticipate prognostic probabilities in LUAD. (a) Univariate and multivariate association of the three-gene prognostic model and clinical characteristics with overall survival. Red represented statistical significance, and blue represented no statistical significance. (b) Nomogram predicting 1-, 3-, and 5-year OS for LUAD patients. The nomogram was applied by adding up the points identified on the point scale of each variable. The total points projected on the bottom scales indicate the probability of 1-, 3-, and 5-year OS. (c) The calibration curve for predicting 1-, 3-, and 5-y OS of LUAD patients. (d) The DCA curves could intuitively evaluate the clinical benefit of the nomogram and the scope of application of the nomogram to obtain clinical benefits. (e) Time-dependent ROC curve analysis evaluated the accuracy of the nomograms. LUAD: lung adenocarcinoma; OS: overall survival; DCA: decision curve analysis.

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