Usefulness of International Normalized Ratio to Albumin Ratio for Evaluation of Mortality in Hepatitis B Virus-Associated Decompensated Cirrhosis
Table 1
Comparisons of demographic and laboratory features between survivors and nonsurvivors in HBV-DeCi patients.
All patients ()
Survivors ()
Nonsurvivors ()
Sex (female/male)
33/133
27/112
6/21
0.944
Age (years)
53.0 (46.0-62.0)
53.0 (47.0-62.0)
54.0 (46.0-62.5)
0.920
Total protein (4.40-7.60 g/dL)
6.16 (5.66-6.73)
6.18 (5.76-6.77)
5.94 (2.29-6.53)
0.086
Albumin (2.80-4.40 g/dL)
3.12 (27.2-3.48)
3.17 (2.82-3.53)
2.89 (2.49-3.13)
0.012
Alanine aminotransferase (5-35 U/L)
30.0 (17.0-48.0)
29.0 (16.3-47.8)
39.0 (28.3-61.3)
0.018
Aspartate aminotransferase (8-40 U/L)
46.0 (28.0-73.0)
41.0 (27.0-70.0)
57.0 (41.8-111.8)
0.005
Serum creatinine (15-77 μmol/L)
73.0 (60.0-85.0)
72.0 (59.3-87.8)
84.0 (62.3-118.0)
0.036
Total bilirubin (0.0-21.0 μmol/L)
41.0 (18.0-103.0)
33.0 (16.3-81.3)
131.0 (74.3-274.8)
<0.001
Blood urea nitrogen (1.4-6.8 mmol/L)
5.7 (4.3-7.5)
5.5 (4.2-7.4)
7.1 (5.2-8.9)
0.038
INR (0.80-1.20)
1.34 (1.18-1.59)
1.30 (1.16-1.52)
1.67 (1.46-2.10)
<0.001
Hemoglobin (113-151 g/L)
104.0 (86.0-121.0)
105.5 (85.0-121.0)
101.0 (93.0-112.5)
0.576
Platelet (101-320 109/L)
66.0 (43.0-112.0)
70.0 (43.0-116.5)
63.0 (49.8-82.5)
0.382
PTAR
0.44 (0.36-0.58)
0.43 (0.35-0.54)
0.62 (0.55-0.82)
<0.001
MELD score
11.41 (6.77-17.06)
10.28 (5.93-14.33)
20.33 (17.27-22.67)
<0.001
Data are expressed as number or median (interquartile range). Abbreviations: HBV-DeCi = hepatitis B virus-associated decompensated cirrhosis; INR = international normalized ratio; PTAR = prothrombin time-international normalized ratio to albumin ratio; MELD = Model for End-stage Liver Disease.
