Combination Therapy of Chemoembolization and Hepatic Arterial Infusion Chemotherapy in Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis Compared with Chemoembolization Alone: A Propensity Score-Matched Analysis

Table 4

Comparison of efficacy of TACE-HAIC with TACE group based on tumor response.

Response (by mRECIST)	Pooled cohort ()			Matched cohort ()
	cTACE ()	cTACE+HAIC ()	value	cTACE ()	cTACE+HAIC ()	Value
Complete	0 (0.0)	3 (3.5)	<0.001	0 (0.0)	3 (5.0)	<0.001
Partial	4 (5.8)	18 (20.9)	0.001	2 (3.3)	16 (26.7)	<0.001
Stable disease	33 (47.8)	47 (54.7)	0.007	31 (51.7)	30 (50.0)	0.855
Progressive disease	32 (46.4)	18 (20.9)	0.010	27 (45.0)	11 (18.3)	<0.001
Objective response rate	4 (5.8)	21 (24.4)	0.002	2 (3.3)	19 (31.7)	<0.001
Disease control rate	37 (53.6)	68 (79.1)	0.001	33 (55.0)	49 (81.7)	0.002

TACE: transcatheter arterial chemoembolization; HAIC: hepatic arterial infusion chemotherapy; mRECIST: modified response evaluation criteria in solid tumors. . . Statistical significance was assessed with the test or Fisher’s exact test.