Pharmacological Evaluation of Antipyretic and Antioxidant Activities of 80% Methanol Root Extract and Derived Solvent Fraction of Echinops kebericho M. (Asteraceae) in Mice Model

Table 1

reduction potential of crude, aqueous, ethyl acetate, and chloroform fractions of EK.

Groups	Baseline (°C)	18 hr after yeast(°C)	after treatment (°C, )
			+0.5 hr	+1 hr	+1.5 hr	+2 hr	+2.5 hr	+3 hr
ASA 100 mg/kg	37.02
NS 10 ml/kg	37.1
EK 100 mg/kg	37.18
EK 200 mg/kg	36.15
EK 400 mg/kg	36.75
AQ 100 mg/kg	36.8
AQ 200 mg/kg	36.9
AQ 400 mg/kg	36.9
EA 100 mg/kg	36.8
EA 200 mg/kg	36.9
EA 400 mg/kg	36.9
CF 100 mg/kg	36.8
CH 200 mg/kg	36.9
CH 400 mg/kg	36.9

Analysis was performed with one-way ANOVA followed by the Tukey post hoc test. Data was expressed in . . ASA: acetyl salicylic acid (100 ml/kg); NS: normal saline (10 ml/kg); EK 100 mg/kg: Echinops kebericho extract (100 mg/kg); EK 200 mg/kg: Echinops kebericho extract (200 mg/kg); EK 400 mg/kg: Echinops kebericho extract (400 mg/kg); AQ 100 mg/kg: aqueous fraction (100 mg/kg); AQ 200 mg/kg: aqueous fraction (200 mg/kg); AQ 400 mg/kg: aqueous fraction (400 mg/kg); EA 100 mg/kg: ethyl acetate fraction (100 mg/kg); EA 200 mg/kg: ethyl acetate fraction (200 mg/kg); EA 400 mg/kg: ethyl acetate fraction (400 mg/kg); CH 100 mg/kg: chloroform fraction (100 mg/kg); CH 200 mg/kg: chloroform fraction (200 mg/kg); CH 400 mg/kg: chloroform fraction (400 mg/kg). As compared to +ve control; as compared to −ve control; as compared to 100 mg/kg EK; as compared to 200 mg/kg EK; as compared to 400 mg/kg EK; ; ; .