Pharmacological Evaluation of Antipyretic and Antioxidant Activities of 80% Methanol Root Extract and Derived Solvent Fraction of Echinops kebericho M. (Asteraceae) in Mice Model

Table 2

Percent temperature reduction potentials of crude extract, aqueous, ethyl acetate, and chloroform fractions of E. kebericho.

Groups	+0.5 hr	+1 hr	+1.5 hr	+2 hr	+2.5 hr	+3 hr
ASA 150 mg/kg	1.51	3.42	4.98	6.11	6.63	7.49
EK 100 mg/kg	0.56	1.33	2.14	2.70	3.34	4.12
EK 200 mg/kg	0.70	2.10	3.23	4.27	5.41	6.50
EK 400 mg/kg	1.17	2.61	3.69	4.10	5.95	6.95
AQ 100 mg/kg	0.35	1.04	1.86	2.34	3.20	3.90
AQ 200 mg/kg	0.61	1.92	3.19	4.11	5.07	6.38
AQ 400 mg/kg	1.17	2.56	3.69	5.08	5.95	6.91
EA 100 mg/kg	0.13	0.22	0.61	0.65	0.61	0.92
EA 200 mg/kg	0.52	0.31	1.31	1.70	2.05	2.45
EA 400 mg/kg	0.66	0.88	1.23	1.53	2.02	2.54
CH 100 mg/kg	0.09	0.22	0.61	0.65	0.61	0.92
CH 200 mg/kg	0.52	0.83	1.31	1.70	2.05	2.44
CH 400 mg/kg	0.66	0.87	1.22	1.53	2.02	2.54

Data was expressed as . ; ASA: acetyl salicylic acid (100 mg/kg); NS: normal saline (10 ml/kg); EK 100 mg/kg: Echinops kebericho extract (100 mg/kg); EK 200 mg/kg: Echinops kebericho extract (200 mg/kg); EK 400 mg/kg: Echinops kebericho extract (400 mg/kg); AQ 100 mg/kg: aqueous fraction (100 mg/kg); AQ 200 mg/kg: aqueous fraction (200 mg/kg); AQ 400 mg/kg: aqueous fraction (400 mg/kg); EA 100 mg/kg: ethyl acetate fraction (100 mg/kg); EA 200 mg/kg: ethyl acetate fraction (200 mg/kg); EA 400 mg/kg: ethyl acetate fraction (400 mg/kg); CH 100 mg/kg: chloroform fraction (100 mg/kg); CH 200 mg/kg: chloroform fraction (200 mg/kg); CH 400 mg/kg: chloroform fraction (400 mg/kg). : temperature.