Research Article

Baseline Values and Kinetics of IL-6, Procalcitonin, and TNF-α in Landrace-Large White Swine Anesthetized with Propofol-Based Total Intravenous Anesthesia

Table 3

Variation of cytokines during the 8-hour period.

0 h1 h2 h3 h4 h5 h6 h7 h8 h value

IL-6 (pg/ml)18 (8-23)65 (49-122)89 (46-150)44 (16-352)36 (15-58)2 (0.03-34)17 (0.03-731)34 (17-43)26 (2-778)<0.0001
Procalcitonin (ng/ml)21 (18-24)20 (18-22)28 (17-68)28 (25-105)27 (24-268)30.5 (21-32)35 (22-35)26 (24-28)25 (20-41)0.152
TNF-α (pg/ml)ND25 (22-27)43 (42-45)54 (51-55)36 (34-37)15 (14-16)15 (13-16)NDND<0.001

Values are expressed as median (±SD). Friedman test for repeated measures. TNF-α: tumor necrosis factor alpha; IL-6: interleukin-6; ND: nondetectable.