Plasma-Derived Exosomal hsa-miR-4488 and hsa-miR-1228-5p: Novel Biomarkers for Dermatomyositis-Associated Interstitial Lung Disease with Anti-Melanoma Differentiation-Associated Protein 5 Antibody-Positive Subset

Table 1

Clinical characteristics of enrolled patients.

Item	DM-ILD-MDA5 ab(+)	DM-nonILD-MSA16(-) ()	Healthy controls ()
Female sex	4 (80)	4 (80)	4 (80)
Age (years)
Age at onset (years)			/
Disease duration (months)			/
Cutaneous features	5 (100)	3 (60)	/
Heliotrope rash	4 (80)	3 (60)	/
Gottron papules	4 (80)	0 (0)	/
Gottron sign	4 (80)	0 (0)	/
V-sign rash	1 (20)	2 (40)	/
Shawl sign	0 (0)	2 (40)	/
Cutaneous ulcers	3 (60)	0 (0)	/
Arthralgia/arthritis	3 (60)	1 (20)	/

Values are expressed as the or (%). DM-ILD-MDA5 Ab(+): DM patients with ILDs and anti-melanoma differentiation-associated protein 5 antibody-positive status; DM-nonILD-MSA16(-): DM patients without ILDs who were negative for 16 detectable myositis-specific antibodies; ILD: interstitial lung disease; DM: dermatomyositis.