Screening and Identification of an Immune-Associated lncRNA Prognostic Signature in Ovarian Carcinoma: Evidence from Bioinformatic Analysis

Figure 1

Construction of high and low immune infiltration groups in ovarian carcinoma. (a) Unsupervised clustering of ovarian carcinoma patients from the TCGA cohort using the ssGSEA method from immune cell types. The whole cohort was clustered into the high immune infiltration group (, immunity_H) and low immune infiltration group (, immunity_L). (b) The tumor purity, stromal score, immune score, and ESTIMATE score were assessed using the ESTIMATE algorithm between high and low immune infiltration groups. . (c, d) The expression levels of HLA family members (c) and CD274 (d) were evaluated between high and low immune infiltration groups in the TCGA cohort. . (e) The proportion difference of several immune cells in the two groups was assessed by the CIBERSORT method. TCGA: The Cancer Genome Atlas; HLA: human leukocyte antigen; ssGSEA: single-sample gene set enrichment analysis; N: number; CIBERSORT: Cell-type Identification by Estimating Relative Subsets of RNA Transcripts.

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