Prolonged Maternal Separation Induces the Depression-Like Behavior Susceptibility to Chronic Unpredictable Mild Stress Exposure in Mice

Table 1

Representative schedule^a of stressors used during the one-week intervention.

Day of intervention	Stressor used	Duration
1	Wet sawdust	24 h
2	Water deprivation	24 h
3	No stressor applied	—
4	Flashing light (stroboscopic light, 60 flashes/min)	3 h
5	Restraint (80 cm^3 breathable, transparent, and plastic pipe)	6 h
6	Food deprivation	24 h
7	Foot shock (electric foot shocks, intensity: 1 mA, duration: 4 s, interval: 26 s)	20 min

^aThe weekly schedule was randomly generated based on the above seven stressors.