Identification of Critical Genes and lncRNAs in Osteolysis after Total Hip Arthroplasty and Osteoarthritis by RNA Sequencing

Table 2

Top 10 up- and downregulated DEmRNAs.

Symbol	log2FC	value	FDR	Regulation
OA vs. control
HIST2H4A	2.017903	1.45-12	1.86-08	Up
ZNF778	2.30578	2.34-09	1.50E-05	Up
RAB8A	1.084187	4.61-07	0.001473	Up
MYOM2	3.614517	1.16-05	0.021164	Up
PI3	1.77021	4.16-05	0.05915	Up
VASH1	1.031837	0.000207	0.203576	Up
SNHG28	1.440766	0.000309	0.263506	Up
LILRB3	1.133152	0.000349	0.27883	Up
UPRT	1.107994	0.000428	0.322295	Up
UNC13B	1.407436	0.000467	0.331741	Up
CD8A	-1.49304	2.03-07	0.000865	Down
AL157935.2	-3.11394	2.71-06	0.006946	Down
AL121594.1	-3.12822	4.34-06	0.00926	Down
EPHB4	-2.33741	1.40-05	0.022395	Down
F11R	-1.30037	6.96-05	0.080899	Down
YPEL2	-1.41993	0.000184	0.196205	Down
CHKB-CPT1B	-1.48977	0.00028	0.255821	Down
ZNF80	-1.53824	0.000671	0.393542	Down
EEF1AKMT3	-1.76553	0.000677	0.393542	Down
CD8B	-1.42735	0.000767	0.426828	Down
Osteolysis vs. control
ZNF778	2.261961	6.77-08	0.000222	Up
LILRB3	1.396428	1.23-06	0.003224	Up
MYOM2	3.476227	3.33-06	0.00575	Up
BCORL1	2.051727	1.40-05	0.018296	Up
RTL5	1.812327	1.85-05	0.022092	Up
FOSL2	1.834524	3.50-05	0.026994	Up
CNTNAP3	2.346929	7.26-05	0.047612	Up
MGAM2	2.714451	9.47-05	0.049807	Up
ERV3-1	1.398861	9.50-05	0.049807	Up
TMEM164	1.378476	0.000107	0.053473	Up
TMEM56-RWDD3	-3.54683	9.81-12	1.29-07	Down
AC013489.1	-4.17415	3.51-06	0.00575	Down
PLVAP	-2.61008	2.39-05	0.026097	Down
PPDPF	-2.88183	2.75-05	0.026397	Down
RPS26	-2.22182	2.82-05	0.026397	Down
HBB	-2.40451	3.29-05	0.026994	Down
RGS6	-2.33305	4.89-05	0.035625	Down
EVPL	-3.08781	5.28-05	0.036452	Down
RIOK3	-2.15799	7.94-05	0.049573	Down
LRRN3	-2.13595	8.98-05	0.049807	Down
Osteolysis vs. OA
EPHB4	3.187856	9.59-07	0.003135	Up
RASSF5	1.444879	1.47-05	0.023969	Up
FAM118A	1.406201	4.97-05	0.064931	Up
AL354822.1	2.9104	0.000364	0.250326	Up
AL121594.1	2.129941	0.0004	0.259591	Up
ZNF587	1.181929	0.000736	0.320854	Up
SERPING1	1.589099	0.002698	0.608048	Up
LRP1	1.363794	0.004148	0.796847	Up
CASP10	1.098776	0.004527	0.796847	Up
REC8	1.074025	0.004665	0.796847	Up
MTURN	-1.58117	1.09-05	0.021921	Down
HBB	-2.3627	1.17-05	0.021921	Down
CISD2	-1.29668	6.10-05	0.07251	Down
AC093668.3	-2.78122	6.93-05	0.073252	Down
DDA1	-1.3542	8.91-05	0.08323	Down
AC013489.1	-3.94451	0.000133	0.11567	Down
ARL4A	-1.83919	0.00018	0.147286	Down
EPB41	-1.62564	0.000288	0.221659	Down
CR1L	-1.61874	0.000353	0.250326	Down
DLGAP5	-2.34576	0.000426	0.259591	Down

FC: fold change; FDR: false discovery rate; OA: osteoarthritis.