Ontology ID Description Count Genes MF GO: 0003700 Transcription factor activity, sequence-specific DNA binding 30 0.005212 POU6F1, E2F3, JDP2, POU6F2, NR6A1, SOX4, SOX6, ZEB1, ZBTB16, TBPL2, MEIS2, POU5F1, PAX7, FOXD4, MAF, FOXL2, TBX15, SMAD9, EOMES, ESRRG, ZFP28, STAT1, FOXP2, UHRF1, FOXD4L1, PBX1, FOXC1, FOXI1, KLF4, PEG3 GO: 0043565 Sequence-specific DNA binding 25 2.82E-05 MAF, JDP2, SATB2, FOXL2, NR6A1, ESRRG, EOMES, GRHL3, EN2, SOX6, SIX4, NR4A3, FOXP2, FOXD4L1, MEIS2, POU5F1, PAX7, LHX5, POU4F1, PBX1, FOXC1, FOXI1, LHX9, FOXD4, FOXD4L5 GO:0005509 Calcium ion binding 22 0.022085 ME1, SLC8A1, NCALD, MICU3, SNCA, DUOX1, PCDHGB7, FLG2, SPARC, MMP14, SLIT1, ATP2B2, DGKB, FAT3, SLC24A2, AIF1L, CACNA1E, VCAN, PLCD1, NCAN, CDH10, CSN2 GO: 0042803 Protein homodimerization activity 20 0.075097 XDH, FGFR1, TBX15, CADM2, NR6A1, BIRC5, ZBTB16, NR4A3, ZNF365, STAT1, CDSN, FOXP2, TYMS, TFRC, TENM1, MAPK4, VEGFA, ADRA2C, HPGD, DPP4 GO: 0046982 Protein heterodimerization activity 16 0.023513 CAV1, JDP2, TBX15, SOX4, BIRC5, SOX6, SMC2, MEIS1, FOXP2, AGTR1, TENM1, MAPK4, P2RY1, VEGFA, PBX1, ADRA2C CC GO: 0005886 Plasma membrane 112 5.6E-06 F2RL2, SLC6A1, CADM2, SLC6A3, SNCA, SLC7A8, CASK, AQP4, IL17RB, NRCAM, ATP2B2, S1PR3, AGTR1, DIRAS1, ATP2B4, MALL, KCNK7, GRID2, NEGR1, LIFR, PIM1, COLEC12, ANKRD13B, RCC2, CD300LG, PMP22, UNC13C, SH3GL2, FRAS1, ME1, NCR3LG1, FGFR1, SLC38A4, CAV1, PTH1R, KCNA4, CACNB2, RIMS1, TTYH3, FGG, SERINC5, OPALIN, P2RY1, ADRA2C, PRIMA1, HCN1, VSTM4, OSBPL3, GABRA1, LPP, GABRA5, EPM2A, SLC6A15, NPY5R, EPHA7, SEMA6D, PKP1, SFRP1, RAP1A, ANTXR2, CACNA1E, GNAZ, KCNJ15, OPCML, GLRA2, DUOX1, NBEA, GABBR2, KCNQ5, SLC24A2, GUCY1A2, ANO3, TMEM100, FAM129A, JPH1, DPP4, SGK1, CACNG8, PCDHGB7, PIGR, MMP14, PRKCB, GRM5, ALOX15, CYBRD1, ADAM12, LIMS2, TRIB3, SLC19A3, ZBTB16, GJC1, FNDC4, SLCO1A2, DGKB, GPM6A, FAT3, KRT1, PCSK9, PLCD1, HTR3B, SLC8A1, SLC8A2, KL, MAP1B, SPARC, TFRC, TENM1, CDON, KCNN3, SLC6A6, BAMBI, CDH10 GO: 0005887 Integral component of plasma membrane 53 1.18E-06 F2RL2, KCNJ15, NRG3, SLC6A1, CADM2, SLC6A3, GLRA2, SLC7A8, AQP4, GABBR2, IL17RB, NRCAM, ATP2B2, AGTR1, S1PR3, ATP2B4, KCNK7, SLC24A2, GRID2, MPP1, LIFR, PIGR, MMP14, SLC7A14, GRM5, CLDN1, SLITRK6, FGFR1, SLC38A4, CAV1, PTH1R, KCNA4, CACNB2, SLC19A3, SLCO1A2, P2RY1, ADRA2C, HTR3B, HCN1, SLC8A1, GABRA1, SLC8A2, KL, PTPRZ1, GABRA5, SLC6A15, NPY5R, EPHA7, TFRC, SEMA6D, TENM1, CDON, SLC6A6 GO: 0005576 Extracellular region 43 0.013279 F2RL2, FGFR1, NRG3, C6, SNCA, CXCL9, SPINK5, ISM2, CHIT1, ADCYAP1, ITGBL1, IL17RB, NRCAM, FGG, AGT, CREG2, SFTA3, COL12A1, PDGFD, LOX, FGF1, COL4A4, BMP3, HAPLN1, VSTM4, KL, SPARC, IL24, COL5A3, CCL16, SLIT1, CHRDL1, TFRC, SFRP1, TENM1, VEGFA, ANTXR2, VCAN, WNT11, COL1A1, ADAM12, NCAN, CSN2 GO: 0005615 Extracellular space 37 0.015039 XDH, LYPD3, NRG3, ADAMTS15, SNCA, CXCL9, CHIT1, ADCYAP1, PCSK2, FGG, C1QTNF3, AGT, SOSTDC1, KRT1, COL12A1, PCSK9, PDGFD, LOX, FGF1, INA, BMP3, CES2, KL, PIGR, SPARC, IL24, CCL16, KRT35, SLIT1, ELFN2, TFRC, SFRP1, VEGFA, VCAN, WNT11, COL1A1, CSN2 GO: 0030054 Cell junction 17 0.011212 GABRA1, CACNG8, MAP1B, GLRA2, SNCA, GABRA5, FERMT1, GABBR2, RIMS1, ATP2B2, ATCAY, SHISA9, GRID2, RAP1A, UNC13C, PRIMA1, UNC13A BP GO: 0006351 Transcription, DNA-templated 47 0.059463863 POU6F1, FGFR1, E2F3, JDP2, EZH2, NR6A1, TRIB3, MYEF2, CBX2, SOX6, ZBTB16, ZEB1, MACC1, HOXA2, NPAS3, POU5F1, ZNF697, PAX7, LHX5, PRKAA2, FOXD4, HELLS, NKRF, MAF, SATB1, SATB2, SMAD9, TBX15, ESRRG, EOMES, BIRC5, NR4A3, ZFP28, STAT1, PRKCB, SUV39H2, FOXP2, EYA4, UHRF1, FOXD4L1, BTG2, TENM1, PARP14, MCIDAS, ID4, PEG3, FOXD4L5 GO: 0045944 Positive regulation of transcription from RNA polymerase II promoter 37 8.53E-05 NR6A1, ONECUT2, CASK, SOX4, SOX6, ZEB1, MEIS1, ADCYAP1, HOXA2, MEIS2, POU5F1, PAX7, P2RY1, POU4F1, FGF1, MAF, PHOX2B, FOXL2, SATB2, ESRRG, EOMES, GRHL3, KLF15, NR4A3, EN2, SIX4, STAT1, UHRF1, MCIDAS, CDON, VEGFA, FOXC1, ID4, PBX1, FOXI1, KLF4, PEG3 GO: 0000122 Negative regulation of transcription from RNA polymerase II promoter 32 1.43E-05 FGFR1, JDP2, CAV1, EZH2, SNCA, NR6A1, TRIB3, CBX2, SOX6, ZEB1, ZBTB16, HOXA2, MEIS2, POU5F1, POU4F1, ZFP36, MAF, SATB1, FOXL2, SATB2, TBX15, EOMES, NR4A3, STAT1, FOXP2, SUV39H2, UHRF1, BTG2, VEGFA, ID4, KLF4, PEG3 GO: 0045893 Positive regulation of transcription, DNA-templated 19 0.008447557 CKS1B, E2F3, FOXL2, EOMES, ESRRG, SOX4, SIX4, ZBTB16, STAT1, NPAS3, SFRP1, AGT, MLLT11, LHX5, WNT11, FOXC1, COL1A1, BAMBI, KLF4 GO: 0008284 Positive regulation of cell proliferation 18 0.006934366 FGFR1, E2F3, ACER2, PTH1R, LIFR, SOX4, BIRC5, IL24, ADCYAP1, S1PR3, SFRP1, VEGFA, PBX1, ID4, PDGFD, FGF1, BAMBI, DPP4
