Research Article
Single Immunoglobulin IL-1-Related Receptor (SIGIRR) Gene rs7396562 Polymorphism and Expression Level in Rheumatoid Arthritis
Table 3
Association of SIGIRR rs7396562 polymorphism with laboratory parameters in patients with RA.
| | Variable | Genotype frequency, (%) | | value | Allele frequency, (%) | | value | | rs7396562 | TT | TG | GG | T | G |
| | RF | | Positive | 155 (38.9) | 178 (44.7) | 65 (16.4) | 1.505 | 0.471 | 488 (61.3) | 308 (38.7) | 1.401 | 0.237 | | Negative | 38 (34.9) | 48 (44.0) | 23 (21.1) | 124 (56.9) | 94 (43.1) | | Anti-CCP | | Positive | 157 (37.6) | 184 (44.2) | 76 (18.2) | 1.478 | 0.478 | 498 (59.7) | 336 (40.3) | 1.602 | 0.206 | | Negative | 28 (31.8) | 40 (45.5) | 20 (22.7) | 96 (54.5) | 80 (45.5) |
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RA: rheumatoid arthritis; RF: rheumatoid factor; Anti-CCP: anticyclic citrullinated peptide. Statistically significant ( ). |
