Evaluation of In Vivo Antiulcer Activity of Hydro-Methanol Extract and Solvent Fractions of the Stem Bark of Ficus thonningii (Moraceae) on Rodent Models

Table 3

Antiulcer (antisecretory) effect of the crude extract of F. thonningii on the pylorus ligated-induced ulcer model.

Treatment	Volume of gastric juice	Reduction of vol (%)	Total acidity	Reduction in acidity (%)	pH	Ulcer index (UI)	Reduction in UI (%)
NC		—		—			—
CE100	^a2	55.8	^a3	41.9			33.6
CE200	^a3	63.3	^a3	54.8	^a1	^a1	59.07
CE400	^a3	63.4	^a3	56.4	^a1	^a1	62.1
R50	^a3	89.8	^a3	58.1	^a1		48.5

Values are expressed as (). ¹, ², and ³. NC = vehicle; CE100 = crude extract at 100 mg/kg; CE200 = crude extract at 200 mg/kg; CE400 = crude extract at 400 mg/kg; R50 = ranitidine at 50 mg/kg; ^a = compared with the negative control group; CEFT: crude extract of Ficus thonningii. Statistical comparisons are significant at value < 0.05.