Focal Adhesion Kinase Inhibitor Inhibits the Oxidative Damage Induced by Central Venous Catheter via Abolishing Focal Adhesion Kinase-Protein Kinase B Pathway Activation

Figure 3

Western blot was performed to determine expression of total FAK, Akt, p-FAK Tyr 397, and p-Akt Ser 473. (a, b) The expression of total FAK, p-FAK Tyr 397, total Akt, and p-Akt Ser 473 in the CVC group and CVC+Y15 group. (c, d) The expression levels of p-FAK Tyr 397 and p-Akt Ser 473 at 2-week, 4-week, and 6-week time points were compared. Data are presented as the ( for each time point per group). Statistical significance was set at and was determined by two-way ANOVA analysis was performed using Bonferroni multiple comparison test. .

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