Focal Adhesion Kinase Inhibitor Inhibits the Oxidative Damage Induced by Central Venous Catheter via Abolishing Focal Adhesion Kinase-Protein Kinase B Pathway Activation

Figure 6

Y15 decreased protein levels of p-FAK, Tyr 397, and p-Akt Ser 473. Western blot was performed to determine expression of total FAK, Akt, p-FAK Tyr 397, and p-Akt Ser 473 at 24 h, 48 h, and 72 h. (a, c) The expression of total FAK and p-FAK Tyr 397 in the CVCs+scratches group and CVCs+scratches+Y15 group. (b, d) The protein levels of total Akt and p-Akt Ser 473. .

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