[Retracted] Transcriptional Profiling Uncovers Biologically Significant RNAs and Regulatory Networks in Nucleus Pulposus from Intervertebral Disc Degeneration Patients

Figure 8

Construction of a lncRNA-miRNA-mRNA network for IVDD. (a) Venn diagram showing the intersection between targeted lncRNAs of 8 DEmiRNAs and DElncRNAs in the GSE56081 dataset. (b) The overlap between predicted mRNAs of 8 DEmiRNAs and DEmRNAs in the GSE56081 dataset. (c) A lncRNA-miRNA-mRNA network for IVDD. (d) A PPI network based on the DEmRNAs in the ceRNA network. The red circle suggests upregulated mRNA in IVDD and the blue circle indicates downregulated mRNA in IVDD. (e) The top ten biological processes of DEmRNAs in the ceRNA network. (f) The top ten cellular components of DEmRNAs in the ceRNA network. (g) The top ten molecular functions of DEmRNAs in the ceRNA network. (h) The top ten KEGG pathways of DEmRNAs in the ceRNA network. The more the color tends to be redder, the smaller the value. The size of the circle is proportional to the number of enriched genes.

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