Determination of Renal Distribution of Zinc, Copper, Iron, and Platinum in Mouse Kidney Using LA-ICP-MS

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Treatment</td><td class="align_center">Pt/Cu</td><td class="align_center">Pt/Zn</td><td class="align_center">Zn/Cu</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">Nonreceiving PC-3 and nontreated with cisplatin</td><td class="align_center">—</td><td class="align_center">—</td><td class="align_center">7 (5-20)</td></tr><tr><td class="align_left">Nonreceiving PC-3 and treated with cisplatin</td><td class="align_center">0.6 (0.25-2)</td><td class="align_center">0.2 (0.08-0.4)</td><td class="align_center">4 (2-18)</td></tr><tr><td class="align_left">Receiving PC-3 and nontreated with cisplatin</td><td class="align_center">—</td><td class="align_center">—</td><td class="align_center">1 (4-20)</td></tr><tr><td class="align_left">Receiving PC-3 and treated with cisplatin</td><td class="align_center">0.9 (0.4-4)</td><td class="align_center">0.2 (0.05-0.5)</td><td class="align_center">7 (3-13)</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Summarization of Pt/Cu, Pt/Zn, and Zn/Cu median concentration ratios in homogenized and mineralized kidney samples and concentration range found using LA-ICP-MS (in parenthesis).</div>

BioMed Research International

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Table 1

Table 1: Determination of Renal Distribution of Zinc, Copper, Iron, and Platinum in Mouse Kidney Using LA-ICP-MS 