Lycopene Ameliorates Liver Inflammation and Redox Status in Mice Exposed to Long-Term Cigarette Smoke

Figure 1

Histopathological aspects of the liver. Stain: HE.  μm. 400x magnification. (a) Control group (CG) and (b) oil group (OG), preserved liver parenchyma, presence of hydropic degeneration (black arrow), and preserved sinusoid capillaries (S). (c–f) Lesions found in the group exposed to CS (CSG). (c) Big area occupied by inflammatory reaction (black arrowhead), hydropic degeneration (black arrow), and preserved sinusoid capillaries (S). (d) Granulomatous reaction detail (black arrowhead). (e) Sinusoidal congestion/hyperemia (white arrowhead and hydropic degeneration (black arrow). (g) Group pretreated with lycopene 25 mg/kg/day (L25CSG), hydropic degeneration (black arrow), inflammatory reaction (black arrowhead), and well-preserved sinusoid capillaries (S). (h) Group pretreated with lycopene 50 mg/kg/day (L50CSG), hydropic degeneration (black arrow), and well-preserved sinusoid capillaries (S).

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